Tubulin binding potentially clears up Bortezomib and Carfilzomib differential neurotoxic effect

Abstract Proteasome inhibitors (PIs) represent the gold standard in the treatment of multiple myeloma. Among PIs, Bortezomib (BTZ) is frequently used as first line therapy, but peripheral neuropathy (PN), occurring approximately in 50% of patients, impairs their life, representing a dose-limiting to...

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Bibliographic Details
Main Authors: A. Malacrida, S. Semperboni, A. Di Domizio, A. Palmioli, L. Broggi, C. Airoldi, C. Meregalli, G. Cavaletti, G. Nicolini
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/5bb52f7cbfd047d0957809e366036543
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