Ethoxyquin is neuroprotective and partially prevents somatic and autonomic neuropathy in db/db mouse model of type 2 diabetes

Abstract Ethoxyquin (EQ), a quinolone-based antioxidant, has demonstrated neuroprotective properties against several neurotoxic drugs in a phenotypic screening and is shown to protect axons in animal models of chemotherapy-induced peripheral neuropathy. We assessed the effects of EQ on peripheral ne...

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Autores principales: Ying Liu, Yuan Sun, Osefame Ewaleifoh, Josh Wei, Ruifa Mi, Jing Zhu, Ahmet Hoke, Michael Polydefkis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Q
Acceso en línea:https://doaj.org/article/5c0248390807438bb3db8f0022d81282
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