Convergent NMDA receptor—Pannexin1 signaling pathways regulate the interaction of CaMKII with Connexin-36

Siu et al use FRET imaging in neuronal cell lines to explore the interplay between the gap junction channel protein Connexin-36 (Cx36) and NMDA receptor and Pannexin 1-mediated calcium signaling. They demonstrate that an increase in intracellular calcium promotes binding of CaMKII to Cx36, leading t...

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Autores principales: Ryan C. F. Siu, Anna Kotova, Ksenia Timonina, Christiane Zoidl, Georg R. Zoidl
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5c1a64775f944aa7933d31f56d812d15
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