Toll-like receptor 4 deficiency accelerates the development of insulin-deficient diabetes in non-obese diabetic mice.
<h4>Background/objective</h4>Toll-like receptors (TLR) mediate the recognition of microbial constituents and stress-induced endogenous ligands by the immune system. They may also be involved in the maintenance or break down of tolerance against autologous antigens. The aim of our investi...
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Main Authors: | Elke Gülden, Masaru Ihira, Atsushi Ohashi, Anna Lena Reinbeck, Marina A Freudenberg, Hubert Kolb, Volker Burkart |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/5c6aea1a33e14d68962e75adc416e65c |
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