Genetic basis of hypercholesterolemia in adults

Abstract We investigated monogenic and polygenic causes of hypercholesterolemia in a population-based cohort, excluding secondary hypercholesterolemia, and using an established framework to identify pathogenic variants. We studied 1682 individuals (50.2 ± 8.6 years, 41.3% males) from southeast Minne...

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Autores principales: Seyedmohammad Saadatagah, Merin Jose, Ozan Dikilitas, Lubna Alhabi, Alexandra A. Miller, Xiao Fan, Janet E. Olson, David C. Kochan, Maya Safarova, Iftikhar J. Kullo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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R
Acceso en línea:https://doaj.org/article/5c962de15c504427a84a1f17c57c7dba
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