Nuclear transport signals control cellular localization and function of androgen receptor cofactor p44/WDR77.

The androgen receptor (AR) cofactor p44/WDR77, which regulates expression of a set of androgen target genes, is required for differentiation of prostate epithelium. Aberrant localization of p44/WDR77 in the cytoplasm is associated with prostate tumorigenesis. Here, we describe studies that used the...

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Auteurs principaux: Zhongping Gu, Liran Zhou, Shen Gao, Zhengxin Wang
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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Accès en ligne:https://doaj.org/article/5c9e2c3729f44c5ba9c0a3e60d18bc51
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