Nuclear transport signals control cellular localization and function of androgen receptor cofactor p44/WDR77.
The androgen receptor (AR) cofactor p44/WDR77, which regulates expression of a set of androgen target genes, is required for differentiation of prostate epithelium. Aberrant localization of p44/WDR77 in the cytoplasm is associated with prostate tumorigenesis. Here, we describe studies that used the...
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Autores principales: | Zhongping Gu, Liran Zhou, Shen Gao, Zhengxin Wang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/5c9e2c3729f44c5ba9c0a3e60d18bc51 |
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