Multitrait GWAS to connect disease variants and biological mechanisms.

Multitrait GWAS to connect disease variants and biological mechanisms.

Genome-wide association studies (GWASs) have uncovered a wealth of associations between common variants and human phenotypes. Here, we present an integrative analysis of GWAS summary statistics from 36 phenotypes to decipher multitrait genetic architecture and its link with biological mechanisms. Ou...

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Auteurs principaux: Hanna Julienne, Vincent Laville, Zachary R McCaw, Zihuai He, Vincent Guillemot, Carla Lasry, Andrey Ziyatdinov, Cyril Nerin, Amaury Vaysse, Pierre Lechat, Hervé Ménager, Wilfried Le Goff, Marie-Pierre Dube, Peter Kraft, Iuliana Ionita-Laza, Bjarni J Vilhjálmsson, Hugues Aschard
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
Sujets:
Genetics
QH426-470
Accès en ligne:https://doaj.org/article/5c9ea5db0c81433a97c3f01fff044602
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Internet

https://doaj.org/article/5c9ea5db0c81433a97c3f01fff044602

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