A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria.

A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria.

Mitochondrial membrane biogenesis and lipid metabolism require phospholipid transfer from the endoplasmic reticulum (ER) to mitochondria. Transfer is thought to occur at regions of close contact of these organelles and to be nonvesicular, but the mechanism is not known. Here we used a novel genetic...

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Autores principales: Sujoy Lahiri, Jesse T Chao, Shabnam Tavassoli, Andrew K O Wong, Vineet Choudhary, Barry P Young, Christopher J R Loewen, William A Prinz
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/5ca6c86505044300bbfe011b1d2dcf78
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