Local administration of HMGB-1 promotes bone regeneration on the critical-sized mandibular defects in rabbits

Abstract Reconstruction of a critical-sized osseous defect is challenging in maxillofacial surgery. Despite novel treatments and advances in supportive therapies, severe complications including infection, nonunion, and malunion can still occur. Here, we aimed to assess the use of a beta-tricalcium p...

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Autores principales: Ahmed Monir, Taro Mukaibo, Abdel Basit M. Abd El-Aal, Tomotaka Nodai, Takashi Munemasa, Yusuke Kondo, Chihiro Masaki, Mahasen A. El-Shair, Kou Matsuo, Ryuji Hosokawa
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5cd80a41744f43059bf72386a771eb72
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