Functional memory B cells and long-lived plasma cells are generated after a single Plasmodium chabaudi infection in mice.

Antibodies have long been shown to play a critical role in naturally acquired immunity to malaria, but it has been suggested that Plasmodium-specific antibodies in humans may not be long lived. The cellular mechanisms underlying B cell and antibody responses are difficult to study in human infection...

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Bibliographic Details
Main Authors: Francis Maina Ndungu, Emma Tamsin Cadman, Joshua Coulcher, Eunice Nduati, Elisabeth Couper, Douglas William Macdonald, Dorothy Ng, Jean Langhorne
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2009
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Online Access:https://doaj.org/article/5ce6b9585b2547c6a6346b8af8a95232
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