20-Hydroxyecdysone protects against oxidative stress-induced neuronal injury by scavenging free radicals and modulating NF-κB and JNK pathways.

Oxidative stress plays an important role in the pathological processes of ischemic brain damage. Many antioxidants have been shown to protect against cerebral ischemia injury by inhibiting oxidative stress both in vitro and in vivo. 20-Hydroxyecdysone (20E), an ecdysteroid hormone, exhibits antioxid...

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Autores principales: Jun Hu, Chun Xia Luo, Wei Hua Chu, You An Shan, Zhong-Ming Qian, Gang Zhu, Yan Bing Yu, Hua Feng
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/5ce7ae0c669c40fcb231887b3d4d04a6
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