Rif1 S-acylation mediates DNA double-strand break repair at the inner nuclear membrane

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Rif1 S-acylation mediates DNA double-strand break repair at the inner nuclear membrane

Rif1 is involved in different processes such as telomere homeostasis, DNA replication timing, and DNA double strand break (DSB) repair pathway choice. Here, the authors reveal that Rif1 S-acylation facilitates the accumulation of Rif1 at DSBs, attenuation of DNA end-resection, and DSB repair by non-...

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Détails bibliographiques
Auteurs principaux:	Gabriele A. Fontana, Daniel Hess, Julia K. Reinert, Stefano Mattarocci, Benoît Falquet, Dominique Klein, David Shore, Nicolas H. Thomä, Ulrich Rass
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2019
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/5cf20ca662034689ad49ccb51a846d04
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

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