The brain targeted delivery of programmed cell death 4 specific siRNA protects mice from CRS-induced depressive behavior

Abstract Depression is one of the most common psychiatric disorders. Recently, studies demonstrate that antidepressants generating BDNF not only maintain synaptic signal transmission but also repress neuroinflammatory cytokines such as IL-6 and IL-1β. Therefore, promoting BDNF expression provides a...

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Autores principales: Yufeng Jia, Xiao Zhuang, Yi Zhang, Ming Zhao, Nuo Chen, Wen Li, Faliang Zhu, Chun Guo, Yan Li, Qun Wang, Yuan Li, Lining Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
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Acceso en línea:https://doaj.org/article/5cf2ede67af44817b7d4b847604a0517
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