Pathogenesis of Human Papillomaviruses Requires the ATR/p62 Autophagy-Related Pathway

ABSTRACT High-risk human papillomaviruses (HPVs) constitutively activate the ataxia telangiectasia and Rad3-related (ATR) DNA damage response pathway, and this is required for viral replication. In fibroblasts, activated ATR regulates transcription of inflammatory genes through its negative effects...

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Autores principales: Shiyuan Hong, Yan Li, Paul J. Kaminski, Jorge Andrade, Laimonis A. Laimins
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
HPV
p62
Acceso en línea:https://doaj.org/article/5d0cf5180f0043dbaf1cd79c8ed96a12
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