The SecA motor generates mechanical force during protein translocation

The ATPase SecA drives Sec-dependent protein translocation across the bacterial plasma membrane. Here, the authors combine kinetic translocation measurements with single-molecule force spectroscopy and demonstrate that the SecA motor generates mechanical force to unfold and translocate preproteins.

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Detalles Bibliográficos
Autores principales: Riti Gupta, Dmitri Toptygin, Christian M. Kaiser
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Q
Acceso en línea:https://doaj.org/article/5d1da2b994af4bd8a77f34c5868db326
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