Endocannabinoid signaling regulates the reinforcing and psychostimulant effects of ketamine in mice

Ketamine is used for sedation and treatment of depression, but is also a drug of abuse. Here the authors show that ketamine modulates the endocannabinoid system in mice, and that this may contribute to its psychoactive effects.

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Bibliographic Details
Main Authors: Wei Xu, Hongchun Li, Liang Wang, Jiamei Zhang, Chunqi Liu, Xuemei Wan, Xiaochong Liu, Yiming Hu, Qiyao Fang, Yuanyuan Xiao, Qian Bu, Hongbo Wang, Jingwei Tian, Yinglan Zhao, Xiaobo Cen
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/5d2e1408f3a74c629dd722b4d53c0d12
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