Interplay between maternal Slc6a4 mutation and prenatal stress: a possible mechanism for autistic behavior development

Interplay between maternal Slc6a4 mutation and prenatal stress: a possible mechanism for autistic behavior development

Abstract The low activity allele of the maternal polymorphism, 5HTTLPR, in the serotonin transporter, SLC6A4, coupled with prenatal stress is reported to increase the risk for children to develop autism spectrum disorder (ASD). Similarly, maternal Slc6a4 knock-out and prenatal stress in rodents resu...

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Bibliographic Details
Main Authors: Calvin P. Sjaarda, Patrick Hecht, Amy J. M. McNaughton, Audrina Zhou, Melissa L. Hudson, Matt J. Will, Garth Smith, Muhammad Ayub, Ping Liang, Nansheng Chen, David Beversdorf, Xudong Liu
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/5d4966ad98074f329ef716a81ff3e158
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https://doaj.org/article/5d4966ad98074f329ef716a81ff3e158

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