Model-based deep embedding for constrained clustering analysis of single cell RNA-seq data

Clustering cells based on similarities in gene expression is the first step towards identifying cell types in scRNASeq data. Here the authors incorporate biological knowledge into the clustering step to facilitate the biological interpretability of clusters, and subsequent cell type identification.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Tian Tian, Jie Zhang, Xiang Lin, Zhi Wei, Hakon Hakonarson
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Q
Accès en ligne:https://doaj.org/article/5d61bdf78def44fd9d00e5d1ec5fd2c2
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!