Oncogenic <i>KRAS</i>-Induced Feedback Inflammatory Signaling in Pancreatic Cancer: An Overview and New Therapeutic Opportunities
Pancreatic ductal adenocarcinoma (PDAC) remains highly refractory to treatment. While the <i>KRAS</i> oncogene is present in almost all PDAC cases and accounts for many of the malignant feats of PDAC, targeting KRAS or its canonical, direct effector cascades remains unsuccessful in patie...
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| Autores principales: | , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
MDPI AG
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/5d817c7138c64e199ef506aadd7b6506 |
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