Non-invasive Metabolomic Profiling of Embryo Culture Medium Using Raman Spectroscopy With Deep Learning Model Predicts the Blastocyst Development Potential of Embryos

Non-invasive Metabolomic Profiling of Embryo Culture Medium Using Raman Spectroscopy With Deep Learning Model Predicts the Blastocyst Development Potential of Embryos

Purpose: This study aimed to establish a non-invasive predicting model via Raman spectroscopy for evaluating the blastocyst development potential of day 3 high-quality cleavage stage embryos.Methods: Raman spectroscopy was used to detect the metabolic spectrum of spent day 3 (D3) embryo culture medi...

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Bibliographic Details
Main Authors: Wei Zheng, Shuoping Zhang, Yifan Gu, Fei Gong, Lingyin Kong, Guangxiu Lu, Ge Lin, Bo Liang, Liang Hu
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
embryo viability prediction
metabolomic profiling
multilayer perceptron
non-invasive assessment
Raman spectroscopy
Physiology
QP1-981
Online Access:https://doaj.org/article/5d81e41b5557405aaf5c89f58675b3b4
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https://doaj.org/article/5d81e41b5557405aaf5c89f58675b3b4

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