Anti-JNK2 peptide–siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice

Anti-JNK2 peptide–siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice

Hua Pan,1 Rohun U Palekar,2 Kirk K Hou,3 John Bacon,2 Huimin Yan,3 Luke E Springer,3 Antonina Akk,3 Lihua Yang,3 Mark J Miller,3 Christine TN Pham,3 Paul H Schlesinger,3 Samuel A Wickline1 1Department of Cardiovascular Sciences, USF Health, Morsani College of Medicine, The USF Health Heart Institut...

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Autores principales: Pan H, Palekar RU, Hou KK, Bacon J, Yan H, Springer LE, Akk A, Yang L, Miller MJ, Pham CTN, Schlesinger PH, Wickline SA
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2018
Materias:
siRNA
JNK2
peptide nanoparticles
perfluorocarbon nanoparticles
macrophages
atherosclerosis
plaque
ApoE-/- mice
thrombosis
endothelium
erosions
scavenger receptors
Medicine (General)
R5-920
Acceso en línea:https://doaj.org/article/5d8337ba3ecc4ea281dbbda0cdcefd34
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https://doaj.org/article/5d8337ba3ecc4ea281dbbda0cdcefd34

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