ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane

INPP5E, a phosphoinositide 5-phosphatase, localizes on the ciliary membrane via its C-terminal prenyl moiety, and maintains the distinct ciliary phosphoinositide composition. The ARL3 GTPase contributes to the ciliary membrane localization of INPP5E by stimulating the release of PDE6D bound to preny...

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Autores principales: Sayaka Fujisawa, Hantian Qiu, Shohei Nozaki, Shuhei Chiba, Yohei Katoh, Kazuhisa Nakayama
Formato: article
Lenguaje:EN
Publicado: The Company of Biologists 2021
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Acceso en línea:https://doaj.org/article/5dc95fdd7b6d4a12a441bc7369127e03
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