Chemogenomic analysis reveals key role for lysine acetylation in regulating Arc stability

The activity-regulated cytoskeleton-associated protein (Arc) has been implicated in synaptic plasticity and memory consolidation. Here the authors show that Arc acetylation regulates its stability and identify small molecules that modulate Arc expression.

Guardado en:
Detalles Bibliográficos
Autores principales: Jasmin Lalonde, Surya A. Reis, Sudhir Sivakumaran, Carl S. Holland, Hendrik Wesseling, John F. Sauld, Begum Alural, Wen-Ning Zhao, Judith A. Steen, Stephen J. Haggarty
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/5ddba3c2cdb2426a93470cf04103e35c
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!