Chemogenomic analysis reveals key role for lysine acetylation in regulating Arc stability

The activity-regulated cytoskeleton-associated protein (Arc) has been implicated in synaptic plasticity and memory consolidation. Here the authors show that Arc acetylation regulates its stability and identify small molecules that modulate Arc expression.

Saved in:
Bibliographic Details
Main Authors: Jasmin Lalonde, Surya A. Reis, Sudhir Sivakumaran, Carl S. Holland, Hendrik Wesseling, John F. Sauld, Begum Alural, Wen-Ning Zhao, Judith A. Steen, Stephen J. Haggarty
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Q
Online Access:https://doaj.org/article/5ddba3c2cdb2426a93470cf04103e35c
Tags: Add Tag
No Tags, Be the first to tag this record!