A probabilistic model of local sequence alignment that simplifies statistical significance estimation.
Sequence database searches require accurate estimation of the statistical significance of scores. Optimal local sequence alignment scores follow Gumbel distributions, but determining an important parameter of the distribution (lambda) requires time-consuming computational simulation. Moreover, optim...
Saved in:
| Main Author: | |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2008
|
| Subjects: | |
| Online Access: | https://doaj.org/article/5dfd88e407dc49c6b637624e120208de |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|