Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain

Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain

Lipid droplets (LDs) are fat storage organelles that are initiated and expanded by seipins at ER contact sites. Here the authors show that the C. elegans seipin ortholog SEIP-1 is recruited to these sites by certain dietary fatty acids to support the expansion of a subset of LDs.

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Detalles Bibliográficos
Autores principales: Zhe Cao, Yan Hao, Chun Wing Fung, Yiu Yiu Lee, Pengfei Wang, Xuesong Li, Kang Xie, Wen Jiun Lam, Yifei Qiu, Ben Zhong Tang, Guanghou Shui, Pingsheng Liu, Jianan Qu, Byung-Ho Kang, Ho Yi Mak
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/5e0412232df841dd8f66c2377abdde09
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https://doaj.org/article/5e0412232df841dd8f66c2377abdde09

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