Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain

Lipid droplets (LDs) are fat storage organelles that are initiated and expanded by seipins at ER contact sites. Here the authors show that the C. elegans seipin ortholog SEIP-1 is recruited to these sites by certain dietary fatty acids to support the expansion of a subset of LDs.

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Autores principales:	Zhe Cao, Yan Hao, Chun Wing Fung, Yiu Yiu Lee, Pengfei Wang, Xuesong Li, Kang Xie, Wen Jiun Lam, Yifei Qiu, Ben Zhong Tang, Guanghou Shui, Pingsheng Liu, Jianan Qu, Byung-Ho Kang, Ho Yi Mak
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5e0412232df841dd8f66c2377abdde09
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spelling	oai:doaj.org-article:5e0412232df841dd8f66c2377abdde092021-12-02T17:01:55ZDietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain10.1038/s41467-019-10835-42041-1723https://doaj.org/article/5e0412232df841dd8f66c2377abdde092019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10835-4https://doaj.org/toc/2041-1723Lipid droplets (LDs) are fat storage organelles that are initiated and expanded by seipins at ER contact sites. Here the authors show that the C. elegans seipin ortholog SEIP-1 is recruited to these sites by certain dietary fatty acids to support the expansion of a subset of LDs.Zhe CaoYan HaoChun Wing FungYiu Yiu LeePengfei WangXuesong LiKang XieWen Jiun LamYifei QiuBen Zhong TangGuanghou ShuiPingsheng LiuJianan QuByung-Ho KangHo Yi MakNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhe Cao Yan Hao Chun Wing Fung Yiu Yiu Lee Pengfei Wang Xuesong Li Kang Xie Wen Jiun Lam Yifei Qiu Ben Zhong Tang Guanghou Shui Pingsheng Liu Jianan Qu Byung-Ho Kang Ho Yi Mak Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain
description	Lipid droplets (LDs) are fat storage organelles that are initiated and expanded by seipins at ER contact sites. Here the authors show that the C. elegans seipin ortholog SEIP-1 is recruited to these sites by certain dietary fatty acids to support the expansion of a subset of LDs.
format	article
author	Zhe Cao Yan Hao Chun Wing Fung Yiu Yiu Lee Pengfei Wang Xuesong Li Kang Xie Wen Jiun Lam Yifei Qiu Ben Zhong Tang Guanghou Shui Pingsheng Liu Jianan Qu Byung-Ho Kang Ho Yi Mak
author_facet	Zhe Cao Yan Hao Chun Wing Fung Yiu Yiu Lee Pengfei Wang Xuesong Li Kang Xie Wen Jiun Lam Yifei Qiu Ben Zhong Tang Guanghou Shui Pingsheng Liu Jianan Qu Byung-Ho Kang Ho Yi Mak
author_sort	Zhe Cao
title	Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain
title_short	Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain
title_full	Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain
title_fullStr	Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain
title_full_unstemmed	Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain
title_sort	dietary fatty acids promote lipid droplet diversity through seipin enrichment in an er subdomain
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/5e0412232df841dd8f66c2377abdde09
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Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain

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