Peptide Bbeta(15-42) preserves endothelial barrier function in shock.

Peptide Bbeta(15-42) preserves endothelial barrier function in shock.

Loss of vascular barrier function causes leak of fluid and proteins into tissues, extensive leak leads to shock and death. Barriers are largely formed by endothelial cell-cell contacts built up by VE-cadherin and are under the control of RhoGTPases. Here we show that a natural plasmin digest product...

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Bibliographic Details
Main Authors: Marion Gröger, Waltraud Pasteiner, George Ignatyev, Ulrich Matt, Sylvia Knapp, Alena Atrasheuskaya, Eugenij Bukin, Peter Friedl, Daniela Zinkl, Renate Hofer-Warbinek, Kai Zacharowski, Peter Petzelbauer, Sonja Reingruber
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2009
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/5e3eace05f4644b8a7d4e2a5920d4940
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https://doaj.org/article/5e3eace05f4644b8a7d4e2a5920d4940

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