ABCB1 protects bat cells from DNA damage induced by genotoxic compounds

Bats possess an extended lifespan compared to most mammals of their size, and have a low cancer incidence. Here the authors show that several bat species exhibit resistance to genotoxic agents that is in part attributable to high expression of the ABCB1 transporter.

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Autores principales: Javier Koh, Yoko Itahana, Ian H. Mendenhall, Dolyce Low, Eunice Xin Yi Soh, Alvin Kunyao Guo, Yok Teng Chionh, Lin-Fa Wang, Koji Itahana
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/5e6e7ed316d54035a1bd7923fee4f815
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