New Host-Directed Therapeutics for the Treatment of <named-content content-type="genus-species">Clostridioides difficile</named-content> Infection

ABSTRACT Frequent and excessive use of antibiotics primes patients to Clostridioides difficile infection (CDI), which leads to fatal pseudomembranous colitis, with limited treatment options. In earlier reports, we used a drug repurposing strategy and identified amoxapine (an antidepressant), doxapra...

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Auteurs principaux: Jourdan A. Andersson, Alex G. Peniche, Cristi L. Galindo, Prapaporn Boonma, Jian Sha, Ruth Ann Luna, Tor C. Savidge, Ashok K. Chopra, Sara M. Dann
Format: article
Langue:EN
Publié: American Society for Microbiology 2020
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Accès en ligne:https://doaj.org/article/5e714ff007e247f187ae4679e2689807
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