New Host-Directed Therapeutics for the Treatment of <named-content content-type="genus-species">Clostridioides difficile</named-content> Infection

New Host-Directed Therapeutics for the Treatment of <named-content content-type="genus-species">Clostridioides difficile</named-content> Infection

ABSTRACT Frequent and excessive use of antibiotics primes patients to Clostridioides difficile infection (CDI), which leads to fatal pseudomembranous colitis, with limited treatment options. In earlier reports, we used a drug repurposing strategy and identified amoxapine (an antidepressant), doxapra...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jourdan A. Andersson, Alex G. Peniche, Cristi L. Galindo, Prapaporn Boonma, Jian Sha, Ruth Ann Luna, Tor C. Savidge, Ashok K. Chopra, Sara M. Dann
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
Clostridioides difficile
germfree mice
host-directed therapeutics
mechanism of action
microbiota
mouse model of infection
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/5e714ff007e247f187ae4679e2689807
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares