High content genome-wide siRNA screen to investigate the coordination of cell size and RNA production

Measurement(s) nascent RNA • Image • S phase • nucleolus organization • Cellular Morphology • Cell Cycle Phase Technology Type(s) metabolic labelling: 5-ethynyl uridine • spinning-disk confocal microscope • supervised machine learning • Image Processing Factor Type(s) gene expression Sample Characte...

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Autores principales: Micha Müller, Lucas Pelkmans, Scott Berry
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5e742d8bf47449b5b7fbed4b1f730cfe
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