High content genome-wide siRNA screen to investigate the coordination of cell size and RNA production
Measurement(s) nascent RNA • Image • S phase • nucleolus organization • Cellular Morphology • Cell Cycle Phase Technology Type(s) metabolic labelling: 5-ethynyl uridine • spinning-disk confocal microscope • supervised machine learning • Image Processing Factor Type(s) gene expression Sample Characte...
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Nature Portfolio
2021
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oai:doaj.org-article:5e742d8bf47449b5b7fbed4b1f730cfe2021-12-02T16:10:46ZHigh content genome-wide siRNA screen to investigate the coordination of cell size and RNA production10.1038/s41597-021-00944-52052-4463https://doaj.org/article/5e742d8bf47449b5b7fbed4b1f730cfe2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41597-021-00944-5https://doaj.org/toc/2052-4463Measurement(s) nascent RNA • Image • S phase • nucleolus organization • Cellular Morphology • Cell Cycle Phase Technology Type(s) metabolic labelling: 5-ethynyl uridine • spinning-disk confocal microscope • supervised machine learning • Image Processing Factor Type(s) gene expression Sample Characteristic - Organism HeLa cell Sample Characteristic - Environment cell culture Machine-accessible metadata file describing the reported data: https://doi.org/10.6084/m9.figshare.14332916Micha MüllerLucas PelkmansScott BerryNature PortfolioarticleScienceQENScientific Data, Vol 8, Iss 1, Pp 1-13 (2021) |
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Science Q Micha Müller Lucas Pelkmans Scott Berry High content genome-wide siRNA screen to investigate the coordination of cell size and RNA production |
description |
Measurement(s) nascent RNA • Image • S phase • nucleolus organization • Cellular Morphology • Cell Cycle Phase Technology Type(s) metabolic labelling: 5-ethynyl uridine • spinning-disk confocal microscope • supervised machine learning • Image Processing Factor Type(s) gene expression Sample Characteristic - Organism HeLa cell Sample Characteristic - Environment cell culture Machine-accessible metadata file describing the reported data: https://doi.org/10.6084/m9.figshare.14332916 |
format |
article |
author |
Micha Müller Lucas Pelkmans Scott Berry |
author_facet |
Micha Müller Lucas Pelkmans Scott Berry |
author_sort |
Micha Müller |
title |
High content genome-wide siRNA screen to investigate the coordination of cell size and RNA production |
title_short |
High content genome-wide siRNA screen to investigate the coordination of cell size and RNA production |
title_full |
High content genome-wide siRNA screen to investigate the coordination of cell size and RNA production |
title_fullStr |
High content genome-wide siRNA screen to investigate the coordination of cell size and RNA production |
title_full_unstemmed |
High content genome-wide siRNA screen to investigate the coordination of cell size and RNA production |
title_sort |
high content genome-wide sirna screen to investigate the coordination of cell size and rna production |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/5e742d8bf47449b5b7fbed4b1f730cfe |
work_keys_str_mv |
AT michamuller highcontentgenomewidesirnascreentoinvestigatethecoordinationofcellsizeandrnaproduction AT lucaspelkmans highcontentgenomewidesirnascreentoinvestigatethecoordinationofcellsizeandrnaproduction AT scottberry highcontentgenomewidesirnascreentoinvestigatethecoordinationofcellsizeandrnaproduction |
_version_ |
1718384413183574016 |