Enantioselective acyl transfer catalysis by a combination of common catalytic motifs and electrostatic interactions

Nucleophilic catalysts are widely used for acyl transfer reactions, but chiral variants can be difficult to design or synthesise. Here, the authors report catalysts with chirality imparted from a binaphtyl moiety with tert-alcohol unit that show both high activity and enantioselectivity for a range...

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Auteurs principaux: Hiroki Mandai, Kazuki Fujii, Hiroshi Yasuhara, Kenko Abe, Koichi Mitsudo, Toshinobu Korenaga, Seiji Suga
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/5e7f35966c0a4cdb94c85844b7113628
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