Enantioselective acyl transfer catalysis by a combination of common catalytic motifs and electrostatic interactions
Nucleophilic catalysts are widely used for acyl transfer reactions, but chiral variants can be difficult to design or synthesise. Here, the authors report catalysts with chirality imparted from a binaphtyl moiety with tert-alcohol unit that show both high activity and enantioselectivity for a range...
Guardado en:
| Autores principales: | , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2016
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/5e7f35966c0a4cdb94c85844b7113628 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | Nucleophilic catalysts are widely used for acyl transfer reactions, but chiral variants can be difficult to design or synthesise. Here, the authors report catalysts with chirality imparted from a binaphtyl moiety with tert-alcohol unit that show both high activity and enantioselectivity for a range of acyl transfer reactions. |
|---|