Experimental and thermodynamic modeling decitabine anti cancer drug solubility in supercritical carbon dioxide

Abstract Design and development of efficient processes for continuous manufacturing of solid dosage oral formulations is of crucial importance for pharmaceutical industry in order to implement the Quality-by-Design paradigm. Supercritical solvent-based manufacturing can be utilized in pharmaceutical...

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Autores principales: Mahboubeh Pishnamazi, Samyar Zabihi, Sahar Jamshidian, Fatemeh Borousan, Ali Zeinolabedini Hezave, Azam Marjani, Saeed Shirazian
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5e83d8309bbc4e50a184c234f8cc4a5a
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