Epigenetic silencing of peroxisome proliferator-activated receptor γ is a biomarker for colorectal cancer progression and adverse patients' outcome.

Epigenetic silencing of peroxisome proliferator-activated receptor γ is a biomarker for colorectal cancer progression and adverse patients' outcome.

The relationship between peroxisome proliferator-activated receptor γ (PPARG) expression and epigenetic changes occurring in colorectal-cancer pathogenesis is largely unknown. We investigated whether PPARG is epigenetically regulated in colorectal cancer (CRC) progression. PPARG expression was asses...

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Autores principales: Massimo Pancione, Lina Sabatino, Alessandra Fucci, Vincenzo Carafa, Angela Nebbioso, Nicola Forte, Antonio Febbraro, Domenico Parente, Concetta Ambrosino, Nicola Normanno, Lucia Altucci, Vittorio Colantuoni
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/5eb28233d0a44bc59483ddea5d682d84
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https://doaj.org/article/5eb28233d0a44bc59483ddea5d682d84

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