CHARACTERISTICS OF SIGNALING PATHWAYS MEDIATING A CYTOTOXIC EFFECT OF DENDRITIC CELLS UPON ACTIVATED Т LYMPHOCYTES AND NK CELLS
Abstract. Cytotoxic/pro-apoptogenic effects of IFNα-induced dendritic cells (IFN-DCs) directed against Т-lymphocytes and NK cells were investigated in healthy donors. Using an allogenic MLC system, it was revealed that IFN-DCs induce apoptosis of both activated CD4+ and CD8+ T-lymphocytes, and NK ce...
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Autores principales: | , , , , , |
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Formato: | article |
Lenguaje: | RU |
Publicado: |
SPb RAACI
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/5ebb326fc78d4bac95d260975d016164 |
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