Vav2 catalysis-dependent pathways contribute to skeletal muscle growth and metabolic homeostasis

Skeletal muscle plays a key role in regulating systemic glucose and metabolic homeostasis. Here, the authors show that the catalytic activity of Vav2, an activator of Rho GTPases, modulates those processes by favoring the responsiveness of this tissue to insulin and related factors.

Saved in:
Bibliographic Details
Main Authors: Sonia Rodríguez-Fdez, L. Francisco Lorenzo-Martín, Isabel Fernández-Pisonero, Begoña Porteiro, Christelle Veyrat-Durebex, Daniel Beiroa, Omar Al-Massadi, Antonio Abad, Carlos Diéguez, Roberto Coppari, Rubén Nogueiras, Xosé R. Bustelo
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Q
Online Access:https://doaj.org/article/5edbd9861e1747dd8edfd43d21bc579c
Tags: Add Tag
No Tags, Be the first to tag this record!