Acute EPA-induced learning and memory impairment in mice is prevented by DHA

Acute EPA-induced learning and memory impairment in mice is prevented by DHA

Acute administration of EPA impairs learning and memory and hippocampal LTP in mice that was mediated through enhancing GABAergic transmission via the 5-HT6R. DHA can prevent EPA-induced impairments at a ratio of EPA to DHA similar to that in marine fish oil via the 5-HT2CR.

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Autores principales: Ji-Hong Liu, Qian Wang, Qiang-Long You, Ze-Lin Li, Neng-Yuan Hu, Yan Wang, Zeng-Lin Jin, Shu-Ji Li, Xiao-Wen Li, Jian-Ming Yang, Xin-Hong Zhu, Yi-Fan Dai, Jiang-Ping Xu, Xiao-Chun Bai, Tian-Ming Gao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/5edff60ffe5c4a1aa0e972347df5b449
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https://doaj.org/article/5edff60ffe5c4a1aa0e972347df5b449

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