Study of factors affecting the in vitro release of diclofenac sodium from hypromelose-based gels

Study of factors affecting the in vitro release of diclofenac sodium from hypromelose-based gels

The aim of our study was to identify factors affecting the in vitro release of diclofenac sodium (DS) from hypromellose-based gels (HPMC). Materials and methods. Gels with HPMC and liquids without HPMC were studied by viscosity-rotating viscometer method and spin probe electron paramagnetic reson...

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Autores principales: Elena Bezuglaya, Hanna Ivashchenko, Nikolay Lyapunov, Igor Zinchenko, Anna Liapunova, Yurij Stolper, Oleksii Liapunov, Tetiana Pukhova
Formato: article
Lenguaje:EN
Publicado: PC Technology Center 2021
Materias:
hypromellose
gel
liquid
diclofenac sodium
isopropyl alcohol
viscosity
rotational correlation time (τ–1)
in vitro release test (ivrt)
Pharmacy and materia medica
RS1-441
Acceso en línea:https://doaj.org/article/5eeae36c2b114ddd9a55884a31867287
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https://doaj.org/article/5eeae36c2b114ddd9a55884a31867287

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