Cooperative inhibition of SNARE-mediated vesicle fusion by α-synuclein monomers and oligomers

Abstract The primary hallmark of Parkinson's disease (PD) is the generation of Lewy bodies of which major component is α-synuclein (α-Syn). Because of increasing evidence of the fundamental roles of α-Syn oligomers in disease progression, α-Syn oligomers have become potential targets for therap...

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Autores principales: Gyeongji Yoo, Sanghun Yeou, Jung Bae Son, Yeon-Kyun Shin, Nam Ki Lee
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5efb5ee1fb0649f6922c3aaf4066f69e
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