Olfactory marker protein directly buffers cAMP to avoid depolarization-induced silencing of olfactory receptor neurons

The physiological role of the olfactory marker protein (OMP) has been elusive. Here, the authors demonstrate that OMP buffers cAMP and modulates cAMP-gated channel activity upon sensory stimulation, maintaining neuronal firing during odour-source searching.

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Auteurs principaux: Noriyuki Nakashima, Kie Nakashima, Akiko Taura, Akiko Takaku-Nakashima, Harunori Ohmori, Makoto Takano
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/5f004020de71409998164819cc158a1c
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