Sign epistasis caused by hierarchy within signalling cascades
Sign epistasis clearly constrains evolution, but its causes are difficult to decipher. Here, the authors study epistasis in a signalling cascade, and arrive at a general criterion and understanding of sign epistasis as arising from the inherent hierarchy between signalling cascade components.
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2018
|
| Subjects: | |
| Online Access: | https://doaj.org/article/5f1ac5638b4b4c4ea6b6271404db04df |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|