A Novel 3D Culture Model of Human ASCs Reduces Cell Death in Spheroid Cores and Maintains Inner Cell Proliferation Compared With a Nonadherent 3D Culture

A Novel 3D Culture Model of Human ASCs Reduces Cell Death in Spheroid Cores and Maintains Inner Cell Proliferation Compared With a Nonadherent 3D Culture

3D cell culture technologies have recently shown very valuable promise for applications in regenerative medicine, but the most common 3D culture methods for mesenchymal stem cells still have limitations for clinical application, mainly due to the slowdown of inner cell proliferation and increase in...

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Bibliographic Details
Main Authors: Liang Luo, Wei Zhang, Jing Wang, Ming Zhao, Kuo Shen, Yanhui Jia, Yan Li, Jian Zhang, Weixia Cai, Dan Xiao, Xiaozhi Bai, Kaituo Liu, Kejia Wang, Yue Zhang, Huayu Zhu, Qin Zhou, Dahai Hu
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
3D culture
organoid
ASCs
3D-ASC
transdifferentiation
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/5f1fbbda193b40ffaf2ffd2533ccb64f
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https://doaj.org/article/5f1fbbda193b40ffaf2ffd2533ccb64f

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