Switched Aβ43 generation in familial Alzheimer’s disease with presenilin 1 mutation
Abstract Presenilin (PS) with a genetic mutation generates abundant β-amyloid protein (Aβ) 43. Senile plaques are formed by Aβ43 in the cerebral parenchyma together with Aβ42 at middle ages. These brains cause the early onset of Alzheimer’s disease (AD), which is known as familial Alzheimer’s diseas...
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| Main Authors: | , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Publishing Group
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/5f2ce92124e54e15a0a0967af4b57009 |
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