Modulation of Aneuploidy in <italic toggle="yes">Leishmania donovani</italic> during Adaptation to Different <italic toggle="yes">In Vitro</italic> and <italic toggle="yes">In Vivo</italic> Environments and Its Impact on Gene Expression

Modulation of Aneuploidy in <italic toggle="yes">Leishmania donovani</italic> during Adaptation to Different <italic toggle="yes">In Vitro</italic> and <italic toggle="yes">In Vivo</italic> Environments and Its Impact on Gene Expression

ABSTRACT Aneuploidy is usually deleterious in multicellular organisms but appears to be tolerated and potentially beneficial in unicellular organisms, including pathogens. Leishmania, a major protozoan parasite, is emerging as a new model for aneuploidy, since in vitro-cultivated strains are highly...

Full description

Saved in:
Bibliographic Details
Main Authors: F. Dumetz, H. Imamura, M. Sanders, V. Seblova, J. Myskova, P. Pescher, M. Vanaerschot, C. J. Meehan, B. Cuypers, G. De Muylder, G. F. Späth, G. Bussotti, J. R. Vermeesch, M. Berriman, J. A. Cotton, P. Volf, J. C. Dujardin, M. A. Domagalska
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
Leishmania
aneuploidy
gene dosage
genomics
life cycle
Microbiology
QR1-502
Online Access:https://doaj.org/article/5f56f02b61fd42dfa374a4c66d46b7e9
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/5f56f02b61fd42dfa374a4c66d46b7e9

Similar Items