The DNA co-vaccination using Sm antigen and IL-10 as prophylactic experimental therapy ameliorates nephritis in a model of lupus induced by pristane.

The DNA co-vaccination using Sm antigen and IL-10 as prophylactic experimental therapy ameliorates nephritis in a model of lupus induced by pristane.

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<h4>Introduction</h4>Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of autoantibodies such as anti-Sm. Studies in patients with SLE and murine models of lupus reveal that the most critical anti-Sm autoantibodies are predominantly direct agains...

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Main Authors: Beatriz Teresita Martín-Márquez, Minoru Satoh, Rogelio Hernández-Pando, Erika Aurora Martínez-García, Marcelo Heron Petri, Flavio Sandoval-García, Oscar Pizano-Martinez, Trinidad García-Iglesias, Fernanda Isadora Corona-Meraz, Monica Vázquez-Del Mercado
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/5f69cb4eb2bf4954bb583b30ad84d7bc
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https://doaj.org/article/5f69cb4eb2bf4954bb583b30ad84d7bc

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