K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation
Receptor-interacting protein kinase 1 (RIPK1) is a critical regulator of cell death but its regulation is unclear. Here, the authors report that RIPK1 kinase activity is regulated by ubiquitination.
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| Auteurs principaux: | , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2019
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/5f6a89e4047e44afb3649cdadbb4c91f |
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| Résumé: | Receptor-interacting protein kinase 1 (RIPK1) is a critical regulator of cell death but its regulation is unclear. Here, the authors report that RIPK1 kinase activity is regulated by ubiquitination. |
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